This is compared to only three published phase III clinical trials of PBT.
There are still uncertainties around the use of PBT that research needs to answer and we have a way to go before we can use PBT with the same confidence and knowledge base that we have amassed for conventional radiotherapy.
Clinical trials are often complex, multi-centre projects carried out across disparate geographical locations and involving large numbers of patients.
With PBT in the UK, there are added complexities for research – the patient pathway will change for patients who will receive PBT at one of the two PBT centres whereas the standard of care treatment will be delivered locally; we need innovative clinical trial methodology and there is a limit on the research capacity at the PBT centres.
The second planned facility is due to open at University College London Hospital in 2020.
Programming Langauge Thesis Implementation - Proton Research Paper